Neuroblox GUI 0.9 beta

Download Neuroblox

Run and explore mechanistic brain-circuit simulations on your own machine. Start from prebuilt models, apply perturbations, and inspect how the simulated system responds.

Choose your downloadPick the build for your operating system below.

Downloads: macOS (400 MB) · Windows (480 MB) · Linux (721 MB)

Free for academic and non-commercial use under the Neuroblox EULA. Commercial licensing: info@neuroblox.ai.

Installation instructions

macOS

Neuroblox launches once you acknowledge that the software was downloaded from the internet.

The app is code-signed through the Apple Developer Program.

Windows

Windows may display a “Windows protected your PC” SmartScreen warning.

  1. On the warning dialog, click More info.
  2. Click the Run anyway button that appears.
  3. Follow the installation wizard as normal.

Windows will remember your choice, so the warning will not appear again for this installer.

Linux

Linux does not block unsigned applications, but on some distributions the .AppImage file may need to be marked as executable before it can run. If it is not executable:

  1. In your file manager, right-click the .AppImage, open its Properties and enable Allow executing file as program. Or run chmod +x neuroblox-*.AppImage from a terminal.
  2. Double-click the file, or launch it from a terminal with ./neuroblox-*.AppImage.

System requirements

macOS
macOS 12 or later, Apple Silicon only. Intel Macs are not supported.
Windows
Windows 10 or later (x86-64).
Linux
A modern 64-bit distribution (x86-64) with a desktop environment.
Memory
16 GB RAM recommended.
Processor
64-bit processor, 4 or more cores.

What you can do

  • Simulate how a drug’s action propagates through neural circuits to biomarker and symptom outcomes (cognition, mood, and behavior)
  • In silico testing of experimental probes, paradigms, and tasks
  • Tune parameters to patient or disorder-specific data